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ACE-031 Nasal Spray

ACE-031 Nasal Spray contains ACE-031 (ramatercept), a recombinant ActRIIB-Fc fusion protein studied in activin and myostatin signalling research, and is available from Direct Sarms in 15ml with 1mg ACE-031 and 30ml with 2mg ACE-031.

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ACE-031 Nasal Spray

ACE-031 (ramatercept) is a recombinant fusion protein in which the extracellular ligand-binding domain of activin receptor type IIB (ActRIIB/ACVR2B) is joined to the Fc portion of human IgG1. Scientific publications have examined ACE-031 with regard to ActRIIB-mediated signalling, covering its interactions with myostatin and other ligands in the transforming growth factor beta (TGF-β) superfamily.

Direct SARMs supplies ACE-031 in a pre-mixed aqueous nasal spray format, available in 15 ml and 30 ml sizes, containing 1 mg and 2 mg of ACE-031 respectively. This liquid presentation provides a defined format for laboratory and analytical research without requiring preparation from a lyophilised material.

Benefits of the nasal spray format

1
The dispensing is pre-measured. Each time the spray mechanism is actuated, it releases a constant volume, which allows for repeatable dispensing when carrying out research procedures.
2
Convenient format. Compact spray bottles are straightforward to store, handle, and transport within an appropriate research environment.
3
Ready to use. Unlike lyophilized peptides, which are provided in vials, nasal spray formulations are in liquid form and do not need to be reconstituted before being handled in the laboratory.
4
Protected storage. The bottle protects the formulation by preventing unnecessary handling and exposure to the environment between research procedures.
5
Simple dispensing. The product can be dispensed easily. With an integrated spraying mechanism, it is not necessary to draw the liquid from a vial, offering a simple way to dispense the formulation during research.

ACE-031 is supplied exclusively for laboratory research use. The information on this page is provided for scientific and educational reference and is based on available published research. This product is not intended for human or veterinary use, diagnosis, treatment, or prevention of any disease or medical condition. It is intended solely for qualified laboratory research and must be handled in accordance with applicable laboratory safety requirements.

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Additional information

Size(s)15ml and 30ml
Amount Per Nasal15ml = 1mg | 30ml = 2mg
Purity99.1%
Molecular FormulaC133H227N43O33
Molecular Weight2956.5 g/mol
Physical FormPre-mixed aqueous solution

General information

Applies to all Direct Sarms research compounds unless noted otherwise on the product.

Storage & handling

Store the nasal spray according to the instructions provided on the product label. Keep the bottle securely closed when not in use and protect it from excessive heat and direct light. Follow any product-specific refrigeration requirements stated on the label.

Shipping & discretion

Fully tracked dispatch with worldwide shipping available. Sent in plain, discreet outer packaging with no product description on the label.

FDA disclosure & intended use

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Research use only — not for human or animal consumption. You must be 18+ and a qualified researcher.

Got a question about this ACE-031 compound?

ACE-031 Nasal Spray is provided as a pre-mixed aqueous solution and not as a lyophilized product which has to be prepared prior to laboratory analysis.

The Direct Sarms ACE-031 Nasal Spray is available in 15 ml and 30 ml formats, containing stated ACE-031 amounts of 1 mg and 2 mg, respectively.

The principal difference is the physical presentation of the material. The nasal format is supplied as a pre-mixed liquid preparation, whereas lyophilized ACE-031 is supplied in a dry, freeze-dried form.

When assessing a product, it is necessary to take into account the protein's identity, its purity, its concentration and the integrity of its formulation, with reference where possible to analytical data specific to the batch. Since ACE-031 is an ActRIIB-Fc fusion protein, the analytical identification must be able to differentiate the desired fusion protein from other similar or incorrectly labelled proteins. This is especially important in view of a published analysis of commercially obtained products labelled as ACE-031 which revealed significant discrepancies in identity.

No. The physical format of a preparation does not by itself establish bioavailability, efficacy, safety or suitability for any particular application. Published ACE-031 research has investigated the molecule as a soluble ActRIIB-Fc fusion protein, and claims concerning an intranasal formulation should not be extrapolated from studies using other administration routes.

Certificate of Analysis

IdentityACE-031CONFORMS
Purity (HPLC)99.1%CONFORMS
Mass (LC-MS)2956.5 g/molCONFORMS
AppearancePre-mixed aqueous solutionCONFORMS